THIS ITEM MAY ONLY BE SHIPPED VIA GROUND Dog and Cat shampoo by DVM Pharmaceuticals. RELIEF Shampoo incorporates colloidal oatmeal , which soothes the aggravating effects of itching discomfort, and pramoxine hydrochloride, 1%, a clinically proven, safe, effective, topical agent for the relief of itching. The formulation is complemented with omega-6 fatty acids for their dermal renourishing effects and is delivered in a soap-free, cosmetically pleasing, cleansing system. Indications: RELIEF Shampoo has been formulated to provide the temporary relief of pruritis (itching discomfort). Dosage and Administration: Shake well before each use. Wet the coat thoroughly. Apply a sufficient amount of RELIEF Shampoo to lather well into the coat. When the entire coat is treated, allow to stand for 5-10 minutes. The contact time is important for optimal antipruritic benefits. Then rinse thoroughly with water. RELIEF Shampoo may be used as often as necessary, or as directed by a veterinarian. Can be used on dogs and cats.